The Lupus Corner, Excel Star Inc presents FLY BUTTERFLY FLY Lupus Awareness Walk. Hosted by Kenner City Councilman Gregory W. Carroll. BenifBenefi the Louisiana Lupus Foundation Approximately 1.5 million Americans have a form of lupus. And at least five million people worldwide, have a form of lupus. Lupus is a systemic autoimmune disease that occurs when your body's immune system attacks your own tissues and organs. Inflammation caused by lupus can affect many different body systems — including your joints, skin, kidneys, blood cells, brain, heart and lungs.